RabGAPs in skeletal muscle function and exercise
نویسندگان
چکیده
منابع مشابه
Calpains, skeletal muscle function and exercise.
1. Skeletal muscle fibres contain ubiquitous (mu-calpain and m-calpain) and muscle-specific (calpain-3) Ca(2+)-dependent proteases. The physiological roles of the calpains are not well understood, although ubiquitous calpains have been associated with apoptosis and myogenesis and calpain-3 is likely involved in sarcomeric remodelling. A defect in the expression of calpain-3 results in limb-gird...
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Muscle adaptation to endurance training involves qualitative changes in intrinsic properties of mitochondria. After training, the ADP sensitivity of miitochondrion is decreased whereas the effect of creatine on respiration is increased. This results in an improved control of aerobic energy production. Acute exercise does not adversely affect mitochondrial function.
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Reactive oxygen species (ROSs) are often associated with damage to cellular functions. ROSs production is indicatives of oxidative stress during physical exercise. Oxidative stress occurs in those circumstances in which free radicals determine a tissue damage or production of toxic and dangerous compounds for tissues. In a relaxation state, antioxidant defense of body may hold under control fre...
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Rheumatoid arthritis (RA) is a chronic, systemic, autoimmune, inflammatory disease associated with cachexia (reduced muscle and increased fat). Although strength-training exercise has been used in persons with RA, it is not clear if it is effective for reducing cachexia. A 46-year-old woman was studied to determine: (i) if resistance exercise could reverse cachexia by improving muscle mass, fib...
متن کاملThe Response of Skeletal Muscle-Expressed Neurotrophins to Acute Resistance Exercise in Male Wistar Rats
Background. BDNF and NT-4/5 have been proposed to be involved in the coordinated adaptations of the neuromuscular system to the elevated level of activity, but an activity-dependent expression of neurotrophins in skeletal muscle is not well established. Objectives. We, therefore, investigated the effect of one session of resistance exercise on mRNA expression of some neurotrophins in Slow and ...
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ژورنال
عنوان ژورنال: Journal of Molecular Endocrinology
سال: 2020
ISSN: 0952-5041,1479-6813
DOI: 10.1530/jme-19-0143